Chemical Communications · 2006 · 63 citations · 16 references
Life SciencesBiochemistryMolecular BiologyCarbohydrate BiochemistryEnzymologyStructure-activity RelationshipsEnzyme InhibitionEnzyme KineticsGlycan StructureO-linked GlycosylationProtein GlycosylationStructure-activity Relationship AnalysisEnzyme Kinetics AssaysEnzyme Kinetics ImagingGlycosidase InhibitionGlycosidase InhibitorsImidazole ChemistryO-linked N-acetylglucosamine ModificationX-ray Diffraction AnalysisX-ray Spectral Analysis
Synthesis of a PUGNAc-imidazole hybrid and its characterization as an inhibitor of human O-GlcNAcase through enzyme kinetics and X-ray structural analysis.
16