Effects of pregnancy and exercise on concentrations of the metabolic markers tumor necrosis factor α and leptin

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Peter Arner, J F, Richard L. Atkinson et al. · Journal of Clinical Investigation · 1995 · 3.5K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

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Life Sciences, Endocrinology, Molecular Biology +17

Changes in Energy Expenditure Resulting from Altered Body Weight

Rudolph L. Leibel, Michael Rosenbaum, Jules Hirsch · New England Journal of Medicine · 1995 · 2K citations · Full text

Life Sciences, Nutritional Sciences, Physiology +14

Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans

Hiroaki Masuzaki, Yoshihiro Ogawa, Norimasa Sagawa et al. · Nature Medicine · 1997 · 1.3K citations

Life Sciences, Endocrinology, Physiology +14