Concepedia

CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

Yajuan Yang, R. Liu, Ruojun Qiu, Y. George Zheng, Wei Huang, Hailong Hu, Qinghong Ji, Hongbin He, Yongfeng Shang, Yaoqin Gong,

Oncogene · 2013 · 118 citations · 76 references

DOI

Concepts

References

76

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 4K citations

, , +14

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

Andrew J. Bannister, Philip Zegerman, Janet F. Partridge et al. · Nature · 2001 · 2.9K citations

, , +12

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

Monika Lachner, Dónal O’Carroll, Stephen Rea et al. · Nature · 2001 · 2.8K citations

, , +9

Role of histone H2A ubiquitination in Polycomb silencing

Hengbin Wang, Liangjun Wang, Hediye Erdjument‐Bromage et al. · Nature · 2004 · 1.8K citations

, , +12