Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy

In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

Dirk Grimm, Joyce Lee, Lora Wang et al. · Journal of Virology · 2008 · 716 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors

Narendra Maheshri, James T. Koerber, Brian K. Kaspar et al. · Nature Biotechnology · 2006 · 544 citations

Life Sciences, Biotechnology, Molecular Biology +15

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

Oliver J. Müller, Felix Kaul, Matthew D. Weitzman et al. · Nature Biotechnology · 2003 · 411 citations

Pharmacy, Molecular Biology, Pharmaceutical Biotechnology +16

Incorporation of Tumor-Targeting Peptides into Recombinant Adeno-associated Virus Capsids

Mirta Grifman, Martin Trepel, Paul Speece et al. · Molecular Therapy · 2001 · 243 citations · Full text

Pharmacy, Molecular Biology, Oncology +16

Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Michael Chang, Jonathan D. Cooper, David E. Sleat et al. · Molecular Therapy · 2008 · 159 citations · Full text

Life Sciences, Neurology, Neuroscience +16