Towards complete and error-free genome assemblies of all vertebrate species

Arang Rhie, Shane McCarthy, Olivier Fédrigo, +122

Nature

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Mark Chaisson, Ashley D. Sanders, Xuefang Zhao, +93

Nature Communications

Haplotype-resolved diverse human genomes and integrated analysis of structural variation

Peter Ebert, Peter A. Audano, Qihui Zhu, +62

Science

Structural VariationGeneticsMolecular BiologyGenomicsHuman Phenotypes +15

In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

Dirk Grimm, Joyce Lee, Lora Wang, +4

Journal of Virology

Viral ReplicationIn Vivo Gene TherapySynthetic VirologyGeneticsImmunology +16

Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome

Derek M. Bickhart, Benjamin D. Rosen, Sergey Koren, +27

Nature Genetics

ChromatinReference AssemblyChromatin StructureDomestic Goat GenomeGenetics +12

Improved reference genome of Aedes aegypti informs arbovirus vector control

Benjamin J. Matthews, Olga Dudchenko, Sarah B. Kingan, +69

Nature

A robust benchmark for detection of germline large deletions and insertions

Justin M. Zook, Nancy F. Hansen, Nathan D. Olson, +47

Nature Biotechnology

EngineeringData ScienceData MiningGermline Large DeletionsComputational Biology +5

A complete reference genome improves analysis of human genetic variation

Sergey Aganezov, Stephanie M. Yan, Daniela C. Soto, +30

Science

GeneticsGenetic EpidemiologyGenomicsHuman VariationRead Mapping +19

High-resolution comparative analysis of great ape genomes

Zev Kronenberg, Ian T. Fiddes, David Gordon, +41

Science

A hybrid approach for de novo human genome sequence assembly and phasing

Yulia Mostovoy, Michal Levy‐Sakin, Jessica Lam, +13

Nature Methods

HybridizationGeneticsHybrid ApproachNatural SciencesSequence Analysis +9