Perturbation of Organogenesis by the Herbicide Atrazine in the Amphibian <i>Xenopus laevis</i>

Abstract

Our results demonstrate that acute atrazine exposure (10-35 mg/L for < or = 48 hr) during early organ morphogenesis disrupts proper organ development in an amphibian model system. The concurrent atrazine-induced apoptosis in the pronephric kidney and midbrain begins to elucidate a mechanism by which atrazine may disrupt developmental processes in nontarget organisms.