Concepedia

Publication | Open Access

Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer

DOIFull Paper Access

380

Citations

39

References

2011

Year

Jermaine Coward, Hagen Kulbe, Probir Chakravarty, David P. Leader, Vessela Vassileva, David A. Leinster, R. Thompson, Tiziana Schioppa, Jeffery Nemeth, Jessica Vermeulen,
Clinical Cancer Research

Abstract

IL-6 stimulates inflammatory cytokine production, tumor angiogenesis, and the tumor macrophage infiltrate in ovarian cancer and these actions can be inhibited by a neutralizing anti-IL-6 antibody in preclinical and clinical studies.

References

YearCitations

Page 1