Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates

Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.

Masashi Mukoyama, Masatoshi Nakajima, Masatsugu Horiuchi et al. · Journal of Biological Chemistry · 1993 · 768 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.

Y Kambayashi, S. Bardhan, Ken Takahashi et al. · Journal of Biological Chemistry · 1993 · 712 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Expression of AT2 receptors in the developing rat fetus.

Eileen F. Grady, Leonardo A. Sechi, Chandi Griffin et al. · Journal of Clinical Investigation · 1991 · 537 citations · Full text

Life Sciences, Developmental Biology, Physiology +12

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

David J. Carini, John V. Duncia, Paul E. Aldrich et al. · Journal of Medicinal Chemistry · 1991 · 431 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Subclasses of angiotensin II binding sites and their functional significance.

David T. Dudley, Robert L. Panek, Terry C. Major et al. · Molecular Pharmacology · 1990 · 378 citations

Medicine, Biochemistry, Pharmacology +11