Concepedia

Prognostic Significance of Circulating IL-10 and IL-6 Serum Levels in Colon Cancer Patients Undergoing Surgery

Gennaro Galizia, Michele Orditura, Ciro Romano, Eva Lieto, Paolo Castellano, L Pelosio, Vincenzo Imperatore, Giuseppe Catalano, Carlo Pignatelli, Ferdinando De Vita

Clinical Immunology · 2002 · 232 citations · 22 references

DOI

Concepts

References

22

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

, , +15

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

Régis Bataille, M Jourdan, X G Zhang et al. · Journal of Clinical Investigation · 1989 · 490 citations · Full text

, , +10

Serum level of interleukin-6 as a prognosis factor in metastatic renal cell carcinoma

1992 · 389 citations

, , +17

Serum interleukin 6 as a prognostic factor in patients with prostate cancer.

J Nakashima, Masaaki Tachibana, Yutaka Horiguchi et al. · PubMed · 2000 · 354 citations

, , +14

Human interleukin-10 can directly inhibit T-cell growth

K Taga, H Mostowski, Giovanna Tosato · Blood · 1993 · 279 citations · Full text

, , +10