Early liraglutide treatment is better in glucose control, β-cell function improvement and mass preservation in db/db mice

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.3K citations · Full text

Life Sciences, Biochemistry, Endocrinology +14

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

Medicine, Endocrinology, Physiology +17

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Gang Xu, Doris A. Stoffers, Joel F. Habener et al. · Diabetes · 1999 · 1.2K citations

Life Sciences, Endocrinology, Physiology +16

Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum

Rolf Mentlein, Baptist Gallwitz, Wolfgang E. Schmidt · European Journal of Biochemistry · 1993 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in Type 2 (non-insulin-dependent) diabetic patients

Michael A. Nauck, N. Kleine, C. �rskov et al. · Diabetologia · 1993 · 1.1K citations · Full text

Medicine, Endocrinology, Internal Medicine +15