5′ end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5′ untranslated region

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

C Gorman, Lindsey Moffat, Bruce H. Howard · Molecular and Cellular Biology · 1982 · 7.8K citations · Full text

Life Sciences, Biology, Molecular Biology +12

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

Life Sciences, Genetics, Molecular Biology +13

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15