Potentiation of the antitumour effect of cyclophosphamide in mice by thalidomide

Thalidomide is an inhibitor of angiogenesis.

Robert J. D’Amato, Michael Loughnan, Evelyn Flynn et al. · Proceedings of the National Academy of Sciences · 1994 · 2.5K citations

Medicine, Pharmacology, Pharmacotherapy +14

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

E P Sampaio, Euzenir Nunes Sarno, Ruth Galilly et al. · The Journal of Experimental Medicine · 1991 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +14

Inhibition of NF-κB Activity by Thalidomide through Suppression of IκB Kinase Activity

Jayne A. Keifer, Denis C. Guttridge, Brian P. Ashburner et al. · Journal of Biological Chemistry · 2001 · 476 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma

Doménico Ribatti, Angelo Vacca, B Nico et al. · British Journal of Cancer · 1999 · 251 citations · Full text

Medicine, Immunology, Oncology +16

Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation.

L Clarke, David J. Waxman · PubMed · 1989 · 179 citations

Medicine, Biochemistry, Pharmacology +17