Concepedia

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951

Emmanuelle Clappier, Sandra Collette, Nathalie Grardel, Stéphane Girard, Lydia Suarez, G Brunie, Sophie Kaltenbach, Karima Yakouben, Françoise Mazingue, A Robert,

Leukemia · 2010 · 128 citations · 33 references

DOI

Concepts

References

33

Activating Mutations of <i>NOTCH1</i> in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee et al. · Science · 2004 · 2.7K citations

, , +17

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

Ching-Hon Pui, Dario Campana, Deqing Pei et al. · New England Journal of Medicine · 2009 · 1.2K citations · Full text

, , +12

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

Adolfo A. Ferrando, Donna Neuberg, Jane Staunton et al. · Cancer Cell · 2002 · 1.1K citations · Full text

, , +16

Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

Hélène Cavé, Jutte van der Werff ten Bosch, Stefan Suciu et al. · New England Journal of Medicine · 1998 · 775 citations · Full text

, , +17

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

Warren S. Pear, Jon C. Aster, Martin Scott et al. · The Journal of Experimental Medicine · 1996 · 712 citations · Full text

, , +13