Concepedia

Prediction of total propofol clearance based on enzyme activities in microsomes from human kidney and liver

Wael S. Al-Jahdari, Koujirou Yamamoto, Haruhiko Hiraoka, Katsunori Nakamura, Fumio Goto, Ryuya Horiuchi

European Journal of Clinical Pharmacology · 2006 · 51 citations · 25 references

DOI

Concepts

References

25

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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In Vitro Glucuronidation Using Human Liver Microsomes and The Pore-Forming Peptide Alamethicin

Michael B. Fisher, Kristina Campanale, Bradley L. Ackermann et al. · Drug Metabolism and Disposition · 2000 · 342 citations

, , +14

[7] Purification and properties of NADPH-Cytochrome P-450 reductase

Henry W. Strobel, John David Dignam · Methods in enzymology on CD-ROM/Methods in enzymology · 1978 · 299 citations

, , +12

Nonspecific binding to microsomes: impact on scale-up of in vitro intrinsic clearance to hepatic clearance as assessed through examination of warfarin, imipramine, and propranolol.

R S Obach · PubMed · 1997 · 281 citations

, , +17

In Vitro Analysis of Human Drug Glucuronidation and Prediction of in Vivo Metabolic Clearance

Matthew G. Soars, Brian Burchell, Robert J. Riley · Journal of Pharmacology and Experimental Therapeutics · 2002 · 228 citations

, , +17