MicroRNA-221 and -222 Regulate Radiation Sensitivity by Targeting the PTEN Pathway

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Medicine, Molecular Genetics, Oncology +16

Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation

Carlos le Sage, Remco Nagel, David A. Egan et al. · The EMBO Journal · 2007 · 813 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1

Tyler E. Miller, Kalpana Ghoshal, Bhuvaneswari Ramaswamy et al. · Journal of Biological Chemistry · 2008 · 750 citations · Full text

Medicine, Molecular Biology, Oncology +17

RETRACTED: miR-221&amp;222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

Michela Garofalo, Gianpiero Di Leva, Giulia Romano et al. · Cancer Cell · 2009 · 735 citations · Full text

Medicine, Molecular Biology, Oncology +16

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

Francesca Fornari, Laura Gramantieri, Manuela Ferracin et al. · Oncogene · 2008 · 641 citations

Medicine, Molecular Biology, Oncology +16