Novel elimination of hydroxylamine and formation of a nickel tetramer on reactions of glutarodihydroxamic acid with model dinickel hydrolases‡

Abstract

Reactions of glutarodihydroxamic acid with the hydrolase enzyme urease models, [Ni2(µ-H2O)(OAc)4(tmen)2] and [Ni2(OAc)3(urea)(tmen)2][OTf], lead to novel hydroxylamine elimination and formation of [Ni2(OAc)2{µ-O(N)(OC)2(CH2)3}(tmen)2][OTf] and the tetramer [Ni4(OAc)2(gluA2)2(tmen)4][OTf]2, respectively, both of which are structurally characterised by X-ray crystallography.