Effect of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues

Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs

Brian W. Metcalf, Philippe Bey, Charles Danzin et al. · Journal of the American Chemical Society · 1978 · 1K citations

Life Sciences, Pharmacology, Biocatalysis +16

Polyamines in Normal and Neoplastic Growth

Peter O’Connor · British Journal of Cancer · 1976 · 550 citations · Full text

Medicine, Cancer Biology, Oncology +8

Biosynthesis of putrescine in the prostate gland of the rat

Anthony E. Pegg, H.G. Williams-Ashman · Biochemical Journal · 1968 · 324 citations · Full text

Life Sciences, Biochemistry, Physiology +7

Concentrations of putrescine and polyamines and their enzymic synthesis during androgen-induced prostatic growth

Anthony E. Pegg, D H Lockwood, H.G. Williams-Ashman · Biochemical Journal · 1970 · 275 citations · Full text

Medicine, Endocrinology, Physiology +15

Studies on ornithine decarboxylase from the liver of thioacetamide-treated rats Purification and some properties

Masayoshi Ono, Hideo Inoue, Fujio Suzuki et al. · Biochimica et Biophysica Acta (BBA) - Enzymology · 1972 · 126 citations

Life Sciences, Pharmacology, Enzymology +3