Prevalence of <i><scp>MED</scp>12</i> mutations in uterine and extrauterine smooth muscle tumours

Abstract

Among uterine smooth muscle tumours, MED12 mutations are frequently present in conventional leiomyomas, but are significantly less common in histological variants of leiomyoma and leiomyosarcoma. In contrast to uterine lesions, none of the extrauterine smooth muscle tumours had MED12 mutations.