Zinc and manganese levels in serum and liver after alcohol feeding and development of fatty cirrhosis in rats.

Abstract

EDITORIAL COMMENT In this experiment, alcohol feeding and choline deficiency produced different effects on zinc and manganese levels in the liver, though these changes could not be correlated with the ability of the liver to detoxicate ammonia. It is suggested that this different effect on trace metals may explain some of the differences between the two types of cirrhosis produced experimentally by alcohol and by choline deficiency.