Concepedia

Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products

Shishir Shishodia, Gautam Sethi, Kwang Seok Ahn, Bharat B. Aggarwal

Biochemical Pharmacology · 2007 · 148 citations · 45 references

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45

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

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Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo

Razqallah Hakem, Anne Hakem, Gordon S. Duncan et al. · Cell · 1998 · 1.3K citations · Full text

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Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

Martine F. Roussel, Richard A. Ashmun, C J Sherr · Cell · 1991 · 1.2K citations

, , +17

Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

Srinivasa M. Srinivasula, Manzoor Ahmad, Teresa Fernandes‐Alnemri et al. · Molecular Cell · 1998 · 1.1K citations · Full text

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Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death

Atan Gross, Xiao Ming Yin, Kun Wang et al. · Journal of Biological Chemistry · 1999 · 1.1K citations · Full text

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