Concepedia

Engineering the isoelectric point of a renal cell carcinoma targeting antibody greatly enhances scFv solubility

Philip Tan, Vano Chu, James E. Stray, Donald K. Hamlin, Dean K. Pettit, D. Scott Wilbur, Robert L. Vessella, Patrick S. Stayton

Immunotechnology · 1998 · 32 citations · 9 references

DOI

Concepts

References

9

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

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Single-Chain Antigen-Binding Proteins

Robert E. Bird, Karl D. Hardman, James W. Jacobson et al. · Science · 1988 · 1.5K citations

, , +13

Replacing the complementarity-determining regions in a human antibody with those from a mouse

Peter Jones, Paul H. Dear, Jefferson Foote et al. · Nature · 1986 · 1.4K citations

, , +13

High resolution functional analysis of antibody-antigen interactions

Lei Jin, B M Fendly, James A. Wells · Journal of Molecular Biology · 1992 · 213 citations

, , +14

Correct disulfide pairing and efficient refolding of detergent-solubilized single-chain Fv proteins from bacterial inclusion bodies

István Kurucz, Julie A. Titus, Carolina R. Jost et al. · Molecular Immunology · 1995 · 74 citations

, , +16