Activation of eosinophils by IL-12 family cytokine IL-27: Implications of the pleiotropic roles of IL-27 in allergic responses

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

Stefan Pflanz, Jackie C. Timans, Jeanne Cheung et al. · Immunity · 2002 · 1.5K citations · Full text

Life Sciences, Cell Biology, Immunology +13

Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system

Jason S. Stumhofer, Arian Laurence, Emma H. Wilson et al. · Nature Immunology · 2006 · 942 citations

Life Sciences, Immunology, Neuroscience +17

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

Ahjoku Amadi‐Obi, Cheng‐Rong Yu, Xuebin Liu et al. · Nature Medicine · 2007 · 849 citations

Medicine, Immunology, Pathology +12

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells

Marcel Batten, Ji Li, Sothy Yi et al. · Nature Immunology · 2006 · 825 citations

Life Sciences, Immunology, Pathology +16

A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells

Amit Awasthi, Yijun Carrier, Jean Pierre Schatzmann Peron et al. · Nature Immunology · 2007 · 802 citations

Life Sciences, Cell Biology, Immunology +17