Dopaminergic Signaling Mediates the Motivational Response Underlying the Opponent Process to Chronic but Not Acute Nicotine

Drug Abuse: Hedonic Homeostatic Dysregulation

George F. Koob, Michel Le Moal · Science · 1997 · 2.5K citations

Medicine, Neuroscience, Psychiatry +17

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

Ian Creese, David R. Burt, Solomon H. Snyder · Science · 1976 · 2.2K citations

Medicine, Neuroscience, Pharmacology +14

An opponent-process theory of motivation: I. Temporal dynamics of affect.

Richard L. Solomon, John Corbit · Psychological Review · 1974 · 1.7K citations

Social Sciences, Behavioral Sciences, Psychology +15

Synaptic Mechanisms Underlie Nicotine-Induced Excitability of Brain Reward Areas

Huibert D. Mansvelder, J. Russel Keath, Daniel S. McGehee · Neuron · 2002 · 694 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Dramatic decreases in brain reward function during nicotine withdrawal

Mark P. Epping-Jordan, Shelly S. Watkins, George F. Koob et al. · Nature · 1998 · 677 citations

Medicine, Neuroscience, Pharmacology +16