George F. Koob

Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress

Tracy L. Bale, Angelo Contarino, George W. Smith et al. · Nature Genetics · 2000 · 850 citations

Psychoneuroimmunology, Stress Hormone, Behavioral Neuroscience +11

Dramatic decreases in brain reward function during nicotine withdrawal

Mark P. Epping-Jordan, Shelly S. Watkins, George F. Koob et al. · Nature · 1998 · 675 citations

Psychiatry, Neurophysiology, Addiction +6

Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats

Friedbert Weiss, Loren H. Parsons, Gery Schulteis et al. · Journal of Neuroscience · 1996 · 459 citations · Full text

Da Release, Substance Use, Social Sciences +20

Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat.

George F. Koob, Susan J. Riley, S. Christine Smith et al. · Journal of Comparative and Physiological Psychology · 1978 · 419 citations

Neuropsychology, Bilateral 6-Hydroxydopamine Lesions, Food Intake +23

The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat

George F. Koob, Hoang Thai Le, Ian Creese · Neuroscience Letters · 1987 · 279 citations

Substance Abuse, Psychoactive Drug, Increases Cocaine Self-administration +8