EFFECT OF CYCLOSPORIN ON HEPATIC REGENERATION.

Abstract

The Capacity of the liver to regenerate after orthotopic liver transplantation is a critical process that is dependent on numerous factors. The effect of drugs, especially immunosuppressive agents, administered during the period when the transplanted liver is most vulnerable is clearly important. We describe preliminary studies examining the effect of cyclosporine A (CsA) on hepatic regeneration when administered before or after 70% partial hepatectomy (PH) in rats.