Concepedia

Synthesis and evaluation of 2-Amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-Amino-9-(3-alkoxycarbonyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines as potential prodrugs of penciclovir

Dae-Kee Kim, Namkyu Lee, Do Hyun Ryu, Young Woo Kim, Jae-Sun Kim, Kieyoung Chang, Guang-Jin Im, Won‐Son Choi, Yong‐Baik Cho, Key H. Kim,

Bioorganic & Medicinal Chemistry · 1999 · 11 citations · 25 references

DOI

Concepts

References

25

Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture

M R Boyd, T. H. Bacon, David Sutton et al. · Antimicrobial Agents and Chemotherapy · 1987 · 238 citations

, , +14

Amino Acid Ester Prodrugs of Acyclovir

Lilia M. Beauchamp, G. Faye Orr, P de Miranda et al. · Antiviral chemistry & chemotherapy · 1992 · 214 citations · Full text

, , +17

Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir]

R. Anthony Vere Hodge, David Sutton, M R Boyd et al. · Antimicrobial Agents and Chemotherapy · 1989 · 210 citations · Full text

, , +12

Pharmacokinetics of Famciclovir in Man

M. A. Pue, Leslie Z. Benet · Antiviral chemistry & chemotherapy · 1993 · 161 citations · Full text

, , +13

Synthesis and antiviral activity of 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]purines

Michael R. Harnden, Richard L. Jarvest, Teresa H. Bacon et al. · Journal of Medicinal Chemistry · 1987 · 155 citations

, , +14