Michael R. Harnden

Synthesis and antiviral activity of 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]purines

Michael R. Harnden, Richard L. Jarvest, Teresa H. Bacon et al. · Journal of Medicinal Chemistry · 1987 · 155 citations

Novel acyclonucleotides: synthesis and antiviral activity of alkenylphosphonic acid derivatives of purines and a pyrimidine

Michael R. Harnden, Ann Parkin, Martin J. Parratt et al. · Journal of Medicinal Chemistry · 1993 · 128 citations

Combinatorial Chemistry, Bioorganic Chemistry, Engineering +22

Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties

Michael R. Harnden, Richard L. Jarvest, Malcolm R. Boyd et al. · Journal of Medicinal Chemistry · 1989 · 100 citations

Medicinal Chemistry, 2-Aminopurine Derivatives, Biochemistry +13

Synthesis and antiviral activity of 9-alkoxypurines. 1. 9-(3-Hydroxypropoxy)- and 9-[3-hydroxy-2-(hydroxymethyl)propoxy]purines

Michael R. Harnden, Paul G. Wyatt, Malcolm R. Boyd et al. · Journal of Medicinal Chemistry · 1990 · 72 citations

Synthesis and in Vivo Evaluation of Prodrugs of 9-[2-(Phosphonomethoxy)ethoxy]adenine

Halina T. Serafinowska, Ray J. Ashton, Stuart Bailey et al. · Journal of Medicinal Chemistry · 1995 · 63 citations

Potential Prodrugs, Medicinal Chemistry, Oral Bioavailability +13