Concepedia

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

Ian G. Ganley, Pui‐Mun Wong, Noor Gammoh, Xuejun Jiang

Molecular Cell · 2011 · 377 citations · 56 references

DOIFull text

Open access

Concepts

References

56

Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

, , +14

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

, , +15

Dissection of the Autophagosome Maturation Process by a Novel Reporter Protein, Tandem Fluorescent-Tagged LC3

Shunsuke Kimura, Takeshi Noda, Tamotsu Yoshimori · Autophagy · 2007 · 2.3K citations · Full text

, , +11

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

Nao Hosokawa, Taichi Hara, Takeshi Kaizuka et al. · Molecular Biology of the Cell · 2009 · 2K citations · Full text

, , +13

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Jayanta Debnath, Senthil K. Muthuswamy, Joan S. Brugge · Methods · 2003 · 2K citations

, , +14