Concepedia

Opposing actions of the progesterone metabolites, 5α-dihydroprogesterone (5αP) and 3α-dihydroprogesterone (3αHP) on mitosis, apoptosis, and expression of Bcl-2, Bax and p21 in human breast cell lines

John P. Wiebe, Michel S. Beausoleil, Guihua Zhang, V Cialacu

The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 38 citations · 39 references

DOI

Concepts

References

39

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10.

Herbert D. Soule, Terry Maloney, Sandra R. Wolman et al. · PubMed · 1990 · 1.6K citations

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p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.

Satomi Matsuoka, Michael C. Edwards, Chang-Ming Bai et al. · Genes & Development · 1995 · 954 citations · Full text

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Effects of p21 <sup>Cip1/Waf1</sup> at Both the G <sub>1</sub> /S and the G <sub>2</sub> /M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

Alexander B. Niculescu, Xinbin Chen, Monique Smeets et al. · Molecular and Cellular Biology · 1998 · 726 citations · Full text

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Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

Santos A. Susín, Hans Kristian Lorenzo, Naoufal Zamzami et al. · The Journal of Experimental Medicine · 1999 · 719 citations · Full text

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

Yan Luo, Jerard Hurwitz, Joan Massagué · Nature · 1995 · 548 citations

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