Concepedia

Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood

Harsha Rajasimha, Patrick F. Chinnery, David C. Samuels

The American Journal of Human Genetics · 2008 · 142 citations · 63 references

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Concepts

References

63

Differentiation and proliferation of hematopoietic stem cells

Megumu Ogawa · Blood · 1993 · 1.4K citations

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Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA

Jack P. Jenuth, Alan C. Peterson, Katherine Fu et al. · Nature Genetics · 1996 · 600 citations

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Demographic influences on mitochondrial DNA lineage survivorship in animal populations

John C. Avise, Joseph E. Neigel, Jonathan Arnold · Journal of Molecular Evolution · 1984 · 581 citations

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Mitochondrial DNA mutations in human colonic crypt stem cells

Robert W. Taylor, Martin Barron, Gillian M. Borthwick et al. · Journal of Clinical Investigation · 2003 · 520 citations · Full text

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Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy.

Agnès Rötig, Stéphane Blanche, Jean‐Paul Bonnefont et al. · Journal of Clinical Investigation · 1990 · 472 citations · Full text

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