Audit of process of antenatal screening for sickle cell disorders at a north London hospital

Abstract

Antenatal screening for haemoglobin disorders (sickle cell disorders and thalassaemias) is now routine.1 Couples who are at risk have a strong preference for prenatal diagnosis during the first trimester,2 but most are identified too late for this in the presenting pregnancy.3 We studied the process of antenatal screening and counselling for sickle cell disorders at this hospital, where 40% of births are in groups at risk. The hospital has a policy of universal antenatal and neonatal screening for haemoglobin disorders. Two community based haemoglobinopathy counsellors are notified when a pregnant carrier is identified and invite the couple within two days to attend for testing of the partner and counselling. About 80% of couples attend. Couples who are interested in prenatal diagnosis are referred to a specialist centre. Thirty one women at risk were identified among those booking for antenatal care between …