Characterization of transgenic mice with overexpression of spermidine synthase

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg, Heide Knauer, Alexandra Schauer et al. · Nature Cell Biology · 2009 · 1.7K citations · Full text

Life Sciences, Biology, Cell Biology +11

Can autophagy promote longevity?

Frank Madeo, Nektarios Tavernarakis, Guido Kroemer · Nature Cell Biology · 2010 · 428 citations

Life Sciences, Cell Biology, Physiology +10

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

James E. Rider, Amy Hacker, C. A. Mackintosh et al. · Amino Acids · 2007 · 315 citations

Life Sciences, Biochemistry, Toxicology +15

The Ornithine Decarboxylase Gene Is Essential for Cell Survival during Early Murine Development

Hélène Pendeville, Nick Carpino, Jean‐Christophe Marine et al. · Molecular and Cellular Biology · 2001 · 278 citations · Full text

Life Sciences, Developmental Biology, Genetics +14

Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.

T G O'Brien, Louis C. Megosh, G Gilliard et al. · PubMed · 1997 · 233 citations

Medicine, Cancer Biology, Oncology +14