Effect of Ascorbic Acid and <i>Allium Sativum</i> on Tissue lead Level in Female <i>Rattus Navigicus</i>

Abstract

The effects of Ascorbic acid (vitamin C) and Allium sativum (garlic) on the lead levels in bone, brain, muscle, liver and kidney tissues of female rats (Rattus navigicus) were investigated. Group I was Control, rats in Groups II – IV were injected intraperitoneally with 100µmol/kg body weight of lead acetate for 7 days. In addition, groups III and IV rats were fed with Allium sativum (200 g/kg diet) and ascorbic acid (500 mg/kg body weight) for 7 days respectively. Results showed the bone to produce a significant (p