A novel HIV-1 antiviral high throughput screening approach for the discovery of HIV-1 inhibitors

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.9K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

Hiroaki Mitsuya, S Broder · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

J S Kimpton, Michael Emerman · Journal of Virology · 1992 · 916 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

Vincent J. Merluzzi, Karl D. Hargrave, Mark E. Labadia et al. · Science · 1990 · 746 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17