Concepedia

Evaluation of MicroRNA375 as a Novel Biomarker for Graft Damage in Clinical Islet Transplantation

Mazhar A. Kanak, Morihito Takita, Rauf Shahbazov, Michael C. Lawrence, Wen Yuan Chung, Ashley R. Dennison, Marlon F. Levy, Bashoo Naziruddin

Transplantation · 2015 · 55 citations · 18 references

DOI

Abstract

Circulating miR375 can be a reliable biomarker to detect graft damage in clinical islet transplantation because serum C-peptide and proinsulin levels are difficult to interpret due to the influence of multiple factors, such as β-cell stress and physiological response.

References

18

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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miRBase: tools for microRNA genomics

Sam Griffiths‐Jones, Harpreet K. Saini, Stijn van Dongen et al. · Nucleic Acids Research · 2007 · 4.4K citations · Full text

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A pancreatic islet-specific microRNA regulates insulin secretion

Matthew N. Poy, Lena Eliasson, Jan Krützfeldt et al. · Nature · 2004 · 2.1K citations

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Serum MicroRNAs Are Promising Novel Biomarkers

Shlomit Gilad, Eti Meiri, Yariv Yogev et al. · PLoS ONE · 2008 · 1.3K citations · Full text

<i>miR-375</i> maintains normal pancreatic α- and β-cell mass

Matthew N. Poy, Jean Hausser, Mirko Trajkovski et al. · Proceedings of the National Academy of Sciences · 2009 · 740 citations · Full text

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