Concepedia

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

Boyi Gan, Jian Hu, Shan Jiang, Yingchun Liu, Ergün Sahin, Zhuang Li, Eliot Fletcher-Sananikone, Simona Colla, Y. Alan Wang, Lynda Chin,

Nature · 2010 · 429 citations · 18 references

DOI

Concepts

References

18

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

Stuart H. Orkin, Leonard I. Zon · Cell · 2008 · 2.5K citations · Full text

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The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Reuben J. Shaw, Katja Lamia, Debbie S. Vasquez et al. · Science · 2005 · 1.9K citations

, , +17

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Reuben J. Shaw, Monica Kosmatka, Nabeel Bardeesy et al. · Proceedings of the National Academy of Sciences · 2004 · 1.8K citations · Full text

, , +17

FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress

Zuzana Tóthová, Ramya Kollipara, Brian J.P. Huntly et al. · Cell · 2007 · 1.5K citations · Full text

, , +16

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

Bong-Hyun Ahn, Hyunseok Kim, Shiwei Song et al. · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

, , +13