Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell · 1992 · 1.8K citations

Medicine, Medicinal Chemistry, Pharmacology +11

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Kazuhiko Umesono, Kevin K. Murakami, Catherine C. Thompson et al. · Cell · 1991 · 1.7K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Nuclear receptor that identifies a novel retinoic acid response pathway

David J. Mangelsdorf, Estelita S. Ong, Jacqueline A. Dyck et al. · Nature · 1990 · 1.5K citations

Life Sciences, Cell Biology, Molecular Biology +14

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

Steven A. Kliewer, Kazuhiko Umesono, David J. Mangelsdorf et al. · Nature · 1992 · 1.5K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

Arthur A. Levin, Laurie J. Sturzenbecker, Sonja Kazmer et al. · Nature · 1992 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +14