Methanodibenzosuberylpiperazines as potent multidrug resistance reversal agents

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

Antimicrobial Resistance Gene, Multidrug-resistant Human Cells, Health Sciences +11

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

James M. Croop, David E. Housman · Cell · 1986 · 1K citations

Complete Cdna Sequence, Antimicrobial Resistance Gene, Medicine +11

In vivo circumvention of P-glycoprotein-mediated multidrug resistance of tumor cells with SDZ PSC 833.

D Boesch, B Jachez, A Pourtier-Manzanedo et al. · PubMed · 1991 · 365 citations

Immunology, Tumor Cells, P388 Cells +18

Kinetics of binding of membrane-active drugs to receptor sites. Diffusion-limited rates for a membrane bilayer approach of 1,4-dihydropyridine calcium channel antagonists to their active site.

David G. Rhodes, J. George Sarmiento, Leo G. Herbette · Molecular Pharmacology · 1985 · 151 citations

Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein

Volker Höll, Monika Kouba, Manfred Dietel et al. · Biochemical Pharmacology · 1992 · 130 citations

Pharmaceutical Science, Biochemistry, Functional Selectivity +8