Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Christopher J. Phiel, Fang Zhang, Eric Yi‐Hsiu Huang et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Modelling schizophrenia using human induced pluripotent stem cells

Kristen Brennand, Anthony Simone, Jessica Jou et al. · Nature · 2011 · 1.4K citations

Life Sciences, Cell Biology, Psychiatry +10

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with β-amyloid deposits in Alzheimer’s disease

Lisa M. Miller, Qi Wang, Tejas Telivala et al. · Journal of Structural Biology · 2005 · 582 citations

Medicine, Neuroscience, Radiology +16

The Mood‐Stabilizing Agent Valproate Inhibits the Activity of Glycogen Synthase Kinase‐3

Li‐Dong Huang, Yiming Jiang, H K Manji · Journal of Neurochemistry · 2000 · 439 citations

Medicine, Molecular Biology, Pharmacology +16

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

Stephen J. Huffaker, Jingshan Chen, Kristin K. Nicodemus et al. · Nature Medicine · 2009 · 256 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14