A double-blind, randomized, placebo-controlled, crossover trial of pentoxifylline for the prevention of chemotherapy-induced oral mucositis

A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck.

Charlotte Jacobs, Gary H. Lyman, E Vélez-García et al. · Journal of Clinical Oncology · 1992 · 633 citations

Medicine, Oncology, Pharmacology +11

Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxofylline

Robert M. Strieter, Daniel G. Remick, P A Ward et al. · Biochemical and Biophysical Research Communications · 1988 · 561 citations

Life Sciences, Biochemistry, Cell Biology +8

Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.

Jeong Han, Patricia A. Thompson, Bruce Beutler · The Journal of Experimental Medicine · 1990 · 508 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Development, testing, and application of the oral assessment guide.

June Eilers, Ann M. Berger, Petersen Mc · PubMed · 1988 · 409 citations

Education, Educational Assessment, Oral Health Sciences +12

Improved complete response rate and survival in advanced head and neck cancer after three-course induction therapy with 120-hour 5-FU infusion and cisplatin

Michael S. Rooney, Julie A. Kish, Jeannie J. Kinzie et al. · Cancer · 1985 · 384 citations

Medicine, Oncology, Chemotherapy +10