Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors

María Pompeiano, José Palacios, Guadalupe Mengod · Molecular Brain Research · 1994 · 877 citations

Life Sciences, Molecular Biology, Neuroscience +13

Evidence for Possible Involvement of 5-HT_2BReceptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications

Richard B. Rothman, Michael H. Baumann, Jason E. Savage et al. · Circulation · 2000 · 710 citations · Full text

Medicine, Cardiology, Pharmacology +17