Concepedia

Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration

David Irwin, Jin Hyen Baek, Kathryn L. Hassell, Rachelle Nuss, Paul Eigenberger, Christina Lisk, Zoe Loomis, Joanne K. Maltzahn, Kurt R. Stenmark, Eva Nozik‐Grayck,

Free Radical Biology and Medicine · 2015 · 63 citations · 23 references

Concepts

Veterinary MedicinePathobiologyPhysiologyInflammationRedox BiochemistryCellular Responses To HypoxiaHemoglobin PhysiologyHypoxia PhysiologyPulmonary HypertensionPulmonary PhysiologyRespiratory PathophysiologyHemoglobin OxidationHypoxia-induced Pulmonary HypertensionPulmonary HemodynamicsPulmonary Oxidative StressPulmonary Responses To HypoxiaPulmonary Vascular RemodelingVascular Remodeling In Hypoxia

References

23

[13] Catalase in vitro

H. Aebi · Methods in enzymology on CD-ROM/Methods in enzymology · 1984 · 25.1K citations

Life Sciences, Biochemistry, Enzymology +3

CRC handbook of methods for oxygen radical research

B.B. Bogomolets · Experimental Gerontology · 1985 · 1.6K citations

Natural Sciences, Biochemistry, Chemistry +13

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen et al. · Blood · 2013 · 689 citations · Full text

Life Sciences, Cell Biology, Pathobiology +10

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation

Eldad A. Hod, Ning Zhang, Set Sokol et al. · Blood · 2010 · 483 citations · Full text

Medicine, Hematology, Immunology +14

Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment of Circulating Mesenchymal Precursors of a Monocyte/Macrophage Lineage

Maria G. Frid, Jacqueline A. Brunetti, Danielle Burke et al. · American Journal Of Pathology · 2006 · 439 citations · Full text

Life Sciences, Cell Biology, Physiology +14