Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism

Maria A. Cavasin, Kim Demos‐Davies, Todd R. Horn, +14

Circulation Research

TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension

Rahul Kumar, Claudia Mickael, Biruk Kassa, +22

Nature Communications

Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension

Douglas D. Lemon, Todd R. Horn, Maria A. Cavasin, +8

Journal of Molecular and Cellular Cardiology

HypertensionMolecular PhysiologyCardiovascular DiseaseBiochemistryMedicine +7

Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress

Danielle J. Reuland, Shadi Khademi, Christopher J. Castle, +4

Free Radical Biology and Medicine

CardiomyopathyHeart FailureBiochemistryLipid PeroxidationPhysiology +9

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

Christian A. Schaer, Jeremy Deuel, Daniela Schildknecht, +12

American Journal of Respiratory and Critical Care Medicine

Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification

David Irwin, Karen M. Helm, Nigel Campbell, +10

American Journal of Physiology-Lung Cellular and Molecular Physiology

Acute Lung InjuryAsthmaEndothelial PotentialNeonatologyLung Inflammation +18

Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension

Beata Wójciak‐Stothard, Vahitha B. Abdul‐Salam, Ka Hou Lao, +14

Circulation

A potential role for reactive oxygen species and the HIF-1α–VEGF pathway in hypoxia-induced pulmonary vascular leak

David Irwin, Joe M. McCord, Eva Nozik‐Grayck, +10

Free Radical Biology and Medicine

InflammationPulmonary CirculationLung InflammationHif-1α–vegf PathwayMedicine +12

Nrf2 activation: A potential strategy for the prevention of acute mountain sickness

Christina Lisk, Joe M. McCord, Swapan K. Bose, +6

Free Radical Biology and Medicine

InflammationAllergyNrf2 ActivationAcute Mountain SicknessImmune Function +3

Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension

James West, Eric D. Austin, Christa Gaskill, +22

American Journal of Physiology-Cell Physiology

HypertensionGeneticsGenetic EpidemiologyHuman PolymorphismPathology +14