Concepedia

Elevated expression of glutaminase confers glucose utilization via glutaminolysis in prostate cancer

Tiejun Pan, Lei Gao, Guojun Wu, Guoqiu Shen, Sen Xie, Handong Wen, Jiarong Yang, Yu Zhou, Zhong Tu, Wei-hong Qian

Biochemical and Biophysical Research Communications · 2014 · 112 citations · 12 references

DOI

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12

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang et al. · Nature · 2009 · 2.1K citations · Full text

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Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

Larry Reitzer, Burton M. Wice, David Kennell · Journal of Biological Chemistry · 1979 · 1.2K citations · Full text

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Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

Matt I. Gross, Susan D. Demo, Jennifer B. Dennison et al. · Molecular Cancer Therapeutics · 2014 · 1.1K citations

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AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

Ning Wu, Bin Zheng, Adam J. Shaywitz et al. · Molecular Cell · 2013 · 670 citations · Full text

, , +11

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1

Meghan J. Seltzer, Bryson D. Bennett, Avadhut D. Joshi et al. · Cancer Research · 2010 · 530 citations · Full text

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