The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis

Immunoregulatory role of interleukin 10 in rheumatoid arthritis.

Peter D. Katsikis, Cong‐Qiu Chu, Fionula M. Brennan et al. · The Journal of Experimental Medicine · 1994 · 530 citations · Full text

Inflammation, Rheumatology, Cytokine +15

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

Iain B. McInnes, Bernard P. Leung, R D Sturrock et al. · Nature Medicine · 1997 · 511 citations

Inflammation, Rheumatology, Cytokine +15

Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils.

Sara Gasperini, Massimo De Marchi, Federica Calzetti et al. · PubMed · 1999 · 306 citations

Immunology, Immune Regulation, Immunologic Mechanism +17

Gene Expression and Production of the Monokine Induced by IFN-γ (MIG), IFN-Inducible T Cell α Chemoattractant (I-TAC), and IFN-γ-Inducible Protein-10 (IP-10) Chemokines by Human Neutrophils

Sara Gasperini, Martina Marchi, Federica Calzetti et al. · The Journal of Immunology · 1999 · 254 citations · Full text

Chemokine Biology, Inflammatory Lung Disease, Immunology +24

Immunomodulation via Novel Use of TLR4 by the Filarial Nematode Phosphorylcholine-Containing Secreted Product, ES-62

Helen S. Goodridge, Fraser A. Marshall, Kathryn J. Else et al. · The Journal of Immunology · 2005 · 236 citations · Full text