Concepedia

The PPARα-FGF21 Hormone Axis Contributes to Metabolic Regulation by the Hepatic JNK Signaling Pathway

Santiago Vernia, Julie Cavanagh-Kyros, Luisa García-Haro, Guadalupe Sabio, Tamera Barrett, Dae Young Jung, Jason K. Kim, Jia Xu, Hennady P. Shulha, Manuel Garber,

Cell Metabolism · 2014 · 195 citations · 50 references

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

, , +17

A central role for JNK in obesity and insulin resistance

Jiro Hirosumi, Gürol Tuncman, Lufen Chang et al. · Nature · 2002 · 3.3K citations

, , +14

FGF-21 as a novel metabolic regulator

Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation · 2005 · 2.1K citations · Full text

, , +17

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Andreas Hörlein, Anders M. Näär, Thorsten Heinzel et al. · Nature · 1995 · 2.1K citations

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Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

Takeshi Inagaki, Paul A. Dutchak, Guixiang Zhao et al. · Cell Metabolism · 2007 · 1.5K citations · Full text

, , +11