Determination of midazolam and its metabolite as a probe for cytochrome P450 3A4 phenotype by liquid chromatography–mass spectrometry

Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms

T D Porter, Minor J. Coon · Journal of Biological Chemistry · 1991 · 679 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Reactions and significance of cytochrome P-450 enzymes

F. Peter Guengerich · Journal of Biological Chemistry · 1991 · 603 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +16

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

Thomas Kronbach, Daniel Mathys, Makoto Umeno et al. · Molecular Pharmacology · 1989 · 535 citations

Medicine, Pharmacology, Biochemical Pharmacology +15

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

Kenneth E. Thummel, Danny D. Shen, Terry Podoll et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 356 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

The pharmacokinetics of midazolam in paediatric patients

K. A. Payne, F J Mattheyse, Deon Liebenberg et al. · European Journal of Clinical Pharmacology · 1989 · 282 citations

Pharmacy, Pharmacokinetics, Pharmacology +9