Expression of differentially phosphorylated Rb and mutant p53 proteins in myeloid leukemia cell lines

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

Life Sciences, Biochemistry, Molecular Biology +9

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Life Sciences, Genetics, Molecular Genetics +16

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

Stephen Friend, René Bernards, Snezna Rogelj et al. · Nature · 1986 · 3K citations · Full text

Medicine, Genetics, Molecular Genetics +12

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

Suzanne J. Baker, Eric R. Fearon, Janice Nigro et al. · Science · 1989 · 2.1K citations

Life Sciences, Genetics, Oncology +16

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

Takashi Takahashi, Marion M. Nau, Itsuo Chiba et al. · Science · 1989 · 1.2K citations

Medicine, Genetics, Molecular Genetics +15