Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson, Davis J. McCarthy, Gordon K. Smyth · Bioinformatics · 2009 · 42.7K citations · Full text

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

Bo Li, Colin N. Dewey · BMC Bioinformatics · 2011 · 22.5K citations · Full text

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Cole Trapnell, Brian A. Williams, Geo Pertea et al. · Nature Biotechnology · 2010 · 16.1K citations

Developmental Biology, Functional Genomics, Rna Biology +10

Differential expression analysis for sequence count data

Simon Anders, Wolfgang Huber · Genome biology · 2010 · 16.1K citations · Full text

Engineering, Genomics, Gene Expression Profiling +19

Mapping and quantifying mammalian transcriptomes by RNA-Seq

A Mortazavi, Brian A. Williams, Kenneth McCue et al. · Nature Methods · 2008 · 14K citations

Functional Genomics, Genetics, Transcriptomics Technology +7