Concepedia

A Haplotype Implicated in Schizophrenia Susceptibility Is Associated with Reduced COMT Expression in Human Brain

Nicholas J. Bray, Paul R. Buckland, Nigel Williams, Hywel Williams, Nadine Norton, Michael J. Owen, Michael O‘Donovan

The American Journal of Human Genetics · 2003 · 339 citations · 26 references

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26

Effect of COMT Val <sup>108/158</sup> Met genotype on frontal lobe function and risk for schizophrenia

Michael Egan, Terry E. Goldberg, Bhaskar Kolachana et al. · Proceedings of the National Academy of Sciences · 2001 · 2.4K citations · Full text

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Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

Herbert M. Lachman, Demitri F. Papolos, Takuya Saito et al. · Pharmacogenetics · 1996 · 1.8K citations

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Enzymatic O-Methylation of Epinephrine and Other Catechols

Julius Axelrod, Robert Tomchick · Journal of Biological Chemistry · 1958 · 1.3K citations · Full text

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Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

Timo Lotta, Jukka Vidgren, Carola Tilgmann et al. · Biochemistry · 1995 · 1.2K citations

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High Rates of Schizophrenia in Adults With Velo-Cardio-Facial Syndrome

Kieran C. Murphy, Lisa Jones, Michael J. Owen · Archives of General Psychiatry · 1999 · 1K citations · Full text

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